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We're proud that SAMBA has chosen Medco to manage your prescription drug benefit for retail and mail-order services. You're in good company. Medco has provided quality prescription drug benefit services to millions of Americans for over 30 years. Included in this packet is your prescription drug ID card. Keep it in your wallet so that it's always handy when you order prescriptions.
Southeast Asian J Trop Med Public Health. 2006 Sep; 37 5 ; : 1040-7. PMID: 17333752 [PubMed - in process], for example, endometreosis.
1. Nadell J, Kosek J. Peliosis hepatitis. Arch Pathol Lab Med 1977; 101: 405-10. Kohr M, Haendige M. Peliosis of the spleen: a rare cause of spontaneous splenic rupture with surgical implications. Surg 1993; 59: 197-9. Allimant P, Mangold J, Froelich N, Zachar D. La peliose esplenique. J Chir Paris ; 1995; 132: 451-3. Makdisi N, Cherian R, Vaneldhuizen PJ, Talley RI, Stark SP, Dixon AY. Fatal peliosis of the liver and spleen in a patient with agnogenic myeloid metaplasia treated with danazol. J Gastroenterol 1995; 90: 317-8. Nesher G, Dollberg L, Zimran A, Hershko C. Hepatosplenic peliosis after danazol and glucocorticoids for ITP. N Engl J Med 1985; 312: 242-3. Ahn YS, Harrington WJ, Simon SR, Mylvaganam R, Pall RM, So AG. Danazlo for the treatment of idiopathic thrombocytopenic purpura. N Engl J Med 1983; 308: 1396-9. George JM, Woolf SH, Raskob GE, et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood 1996; 1-40. 8. Russel J, Cines D. Immune thrombocytopenic purpura, neonatal alloimmunethrombocytopenia, and posttransfusion purpura. In: Hoffman R, Benz EJ jr, Shattil SJ, Furie B, Cohen HJ, Silberstein LE, eds. Hematology: basic principles and practice. New York: Churchill Livingstone, 1995. p. 1849-70. 9. Leong SS, Cazen RA, Yu GSM, Lefevre L, Carson JW. Abdominal visceral peliosis associated with bacillary angiomatosis: ultrastructural evidence of endothelial destruction by bacilli. Arch Pathol Lab Med 1992; 116: 866-71. Perkocha LA, Geaghan SM, Yen TSB, et al. Clinical and pathological features of bacillary peliosis hepatis in association with human immunodeficiency virus infection. N Engl J Med 1990; 323: 1581-8.
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Drug treatment There are two types of drug treatment: i ; Pain killers - these drugs are normally taken during painful periods. E.g. Mefanamic Acid ii ; Hormones - the purpose of hormone therapy is to stop or lighten the periods. There are several different types of hormones which can be used for this purpose: The combined pill used normally or continuously without the 7 day break ; Ranazol - this is given in tablet form and works by stopping the periods. It has several side effects including weight gain, mood changes, unwanted hair and deepening of the voice. Progesterone - there are a variety of different preparations. Again the purpose is to stop the periods. The main side effects are fluid retention and mood changes. LHRH anologues - Zoladex or Prostap ; - these drugs are given as monthly injections. This is the most effective drug treatment. It has the effect of stopping the periods completely. These drugs act by stopping the Pituitary gland stimulating the ovary. Because the ovary stops working temporarily ; , Oestrogen falls to low levels. The side effects of these hormones are, therefore, those of the menopause - hot flushes, sweats, vaginal dryness and mood changes. LHRH anologues with Oestrogen "add back" therapy - LHRH anologues are effective in controlling the symptoms of endometriosis but because of the low levels of Oestrogen produced, they cannot be given for more than six months because of the possible risk of osteoporosis thinning of the bones ; . Oestrogen can be given simultaneously with LHRH anologues reducing these side effects while not reducing their effectiveness.
Q Exempt Prescription not signed by the patient or representative. q Format of signature not acceptable. q Evidence that patient or representative has paid the prescription fee. q Item not properly classified as a contraceptive if submitted in the contraceptive group.
Outsourced R&D The Company has so far outsourced over US$ 2.2 million worth research to Indian service providers. In areas of chemistry, AstraZeneca has been outsourcing activities such as process R&D and intermediaries to Syngene and Strides Arcolabs for shortening drug discovery. Avesthagen and Bangalore Genei have been supporting research programmes focusing on developing proteins and building a genomic library. Bangalore Genei is further supplying restriction enzymes critical to the research activity being conducted by AstaZeneca. Strand Genomics, Genotypic Technologies and SysArris Software have been handling a part of the process integration and informatics applications, respectively and darvon.
22 Heaney A, Collins JSA, Watson RPG, McFarland RJM, Bamford KB, Tham TCK. A prospective randomised trial of a "test-and-treat" policy versus endoscopy based management in young Helicobacter pylori positive patients with ulcer-like dyspepsia, referred to a hospital clinic. Gut 1999; 45: 186-90. Ladabaum U, Chey WD, Scheiman JM, Fendrick AM. Reappraisal of non-invasive management strategies for uninvestigated dyspepsia: a costminimization analysis. Aliment Pharmacol Ther 2002; 16: 1491-501. Vicari JJ, Peek RM, Falk GW, Goldblum JR, Easley KA, Schnell J, et al. The seroprevalence of cagA-positive Helicobacter pylori strains in the spectrum of gastroesophageal reflux disease. Gastroenterology 1998; 115: 50-7. Manes G, Mosca S, Laccetti M, Lioniello M, Balzano A. Helicobacter pylori infection, pattern of gastritis and symptoms in erosive and nonerosive gastroesophageal reflux disease. Scand J Gastrenterol 1999; 34: 658-62. Jaakkimainen RL, Boyle E, Tudiver F. Is Helicobacter pylori associated with non-ulcer dyspepsia and will eradication improve symptoms? A meta-analysis. BMJ 1999; 319: 1040-4.
21. Hsiao GH, Chiu HC. Low-dose danazol in the treatment of livedoid vasculitis. Dermatology. 1997; 194: 251-255. Wakelin SH, Ellis JP, Black MM. Livedoid vasculitis with anticardiolipin antibodies: improvement with danazol. Br J Dermatol. 1998; 139: 935-937. Hoogenberg K, Tupker RA, van Essen LH, Smit AJ, Kallenberg CG. Successful treatment of ulcerating livedo reticularis with infusions of prostacyclin. Br J Dermatol. 1992; 127: 64-66. Tsutsui K, Shirasaki F, Takata M, Takehara K. Successful treatment of livedo vasculitis with beraprost sodium: a possible mechanism of thrombomodulin upregulation. Dermatology. 1996; 192: 120-124. Winkelmann RK, Schroeter AL, Kierland RR, Ryan TM. Clinical studies of livedoid vasculitis: segmental hyalinizing vasculitis ; . Mayo Clin Proc. 1974; 49: 746-750. Choi HJ, Hann SK. Livedo reticularis and livedoid vasculitis responding to PUVA therapy. J Acad Dermatol. 1999; 40: 204-207. Lee JH, Choi HJ, Kim SM, Hann SK, Park YK. Livedoid vasculitis responding to PUVA therapy. Int J Dermatol. 2001; 40: 153-157. LeizoroviczA, HaughMC, ChapuisFR, SamamaMM, BoisselJP.Lowmolecularweight heparin in prevention of perioperative thrombosis. BMJ. 1992; 305: 913-920. Lensing AW, Prins MH, Davidson BL, Hirsh J. Treatment of deep venous thrombosis with low-molecular-weight heparins: a meta-analysis. Arch Intern Med. 1995; 155: 601-607. Goodman SG, Barr A, Sobtchouk A, et al. Low molecular weight heparin decreases rebound ischemia in unstable angina or non-Q-wave myocardial infarction: the Canadian ESSENCE ST segment monitoring substudy. J Coll Cardiol. 2000; 36: 1507-1513 and deltasone.
Suffering and enhance quality of life. We are the only company with leadership positions in both patented and generic pharmaceuticals as well as human vaccines and OTC products. Our businesses are divided on a worldwide basis into the following four operating divisions: Pharmaceuticals brand-name patented pharmaceuticals ; Vaccines and Diagnostics human vaccines and molecular diagnostics ; Sandoz generic pharmaceuticals ; Consumer Health OTC, Animal Health, Gerber and CIBA Vision ; Vaccines and Diagnostics is a new division formed in 2006 following the acquisition of the remaining stake in Chiron Corporation not already held by Novartis. Our Medical Nutrition Business Unit was previously included in the Consumer Health Division, but has been classified as a discontinuing operation as a consequence of an announcement during 2006 to divest this business unit. The Nutrition & Sant activity of this business unit which was divested in e February 2006 has also been classified as a discontinuing operation. In 2006, we achieved Group net sales of $37.0 billion 2005: $32.2 billion ; and net income of $7.2 billion 2005: $6.1 billion ; . Approximately $5.4 billion was invested in R&D 2005: $4.8 billion ; . Headquartered in Basel, Switzerland, we employ approximately 101, 000 associates and have operations in approximately 140 countries around the world. FACTORS AFFECTING RESULTS OF OPERATIONS There are a number of key factors that influence our results of operations and the development of our business. The overall global healthcare market is growing rapidly, due to a combination of socio-economic factors, including aging populations in many developed countries and rapid economic growth in many developing countries, which is leading to a change in lifestyles and a growing demand for better healthcare. At the same time, we are operating in an ever more challenging competitive environment and the healthcare industry is generally subject to significant ongoing pricing pressures. Widespread efforts by both governments and private stakeholders to control and reduce healthcare cost create particular challenges for our Pharmaceuticals Division. To address these challenges, we have established several strategic growth platforms, both with brand-name patented medicines and beyond, including innovation-driven prescription medicines, cost-effective and high-quality generic medicines, leading self-medication OTC ; brands and human vaccines. We have invested heavily into these strategic growth platforms in recent years, including through the acquisitions of Chiron Corporation and NeuTec Pharma plc in 2006 and Hexal AG and Eon Labs, Inc., and the North American Consumer Medicines Business of Bristol-Myers Squibb in 2005. Patent protection and the exclusive right to sell certain products in key markets are particularly important for our Pharmaceuticals Division. The loss of exclusivity with regard to one or more important products e.g. due to patent expiration, generic challenges or competition from new branded products ; can therefore have a significant negative impact on the results of operations of our Pharmaceuticals Division. As a result, our ability to identify and develop new breakthrough products and to bring these products to market is particularly important for our long-term business prospects. To be able to meet this challenge, we have invested heavily in R&D and plan to continue to do so the future. The loss of patent protection for important products by competing pharmaceuticals companies, of course, can also create significant opportunities for our Sandoz Division to market generic versions of such products. Finally, we are constantly exploring ways to improve productivity across the Group, in particular to optimize our Marketing & Sales activities in our Pharmaceuticals Division. The failure or success of these initiatives can have a significant impact on our overall business success. 86.
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Care cost savings of $94 per patient. While this may represent cost savings for health plans and hospitals, the added medication cost will in many cases be passed directly to the patient. The nine-drug regimen mentioned above would cost approximately $300 to $700 month or $3, 600 to $8, 400 year ; , depending on the specific drug formulations used. POLYPHARMACY IS HERE TO STAY The CHARM trial reminds us that despite the evolving surgical treatments and new REFERENCES and desyrel.
Children If possible, quinolone antibiotics should be avoided in childhood because of the effects on cartilage in animals. However, quinolones have not been associated with such toxicity in children despite extensive study. Therefore, the use of a quinolone can be considered if it is felt to be essential for a particular clinical situation. Pregnant women The safety of Loflox during pregnancy has not been established. The elderly In the elderly, dose alteration is unnecessary, unless there is moderate to severe renal failure. Concurrent disease Dose reductions are required in patients with moderate severe renal impairment. 10- Drug interactions Potentially hazardous interactions Mineral antacids magnesium or aluminum containing ; reduce absorption of Loflox. Potentially useful interactions Probenecid has been shown to decrease the elimination of most quinolones. Storage Store below 30 C. Protect from light and moisture. Packaging Boxes of 20 F.C.Tablets.
Realizing that the pain, although unpleasant, is not life-threatening often allows the patient and parents to apply healthier coping strategies and famvir.
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However, many of these coinages have proven to be unstable, and have either fallen out of use or been replaced with pronunciations more in keeping with the original esperanto vocabulary, such as pobo and vato for popo and ato and imovane.
Four small systematic reviews found that all hormonal treatments except dydrogesterone were equally effective, compared with placebo, in reducing pain attributed to endometriosis One systematic review of small RCTs found no evidence that hormonal treatments improved fertility Six months' postoperative treatment with gonadotrophin releasing hormone analogues or a combination of danaol and medroxyprogesterone significantly reduces pain and delays the recurrence of pain compared with placebo, but there is no evidence of an effect of postoperative gonadotrophin releasing hormone analogues on fertility We found insufficient evidence on the effects of laparoscopic uterine nerve ablation in women with pain attributed to endometriosis and on the effects of laparoscopic ablation of deposits on its own One RCT found no evidence that preoperative treatment with gonadotrophin releasing hormone analogues facilitated surgery One RCT found that pain and subfertility caused by ovarian endometrioma were improved more by cystectomy than by drainage operation median interval 19 months v 9.5 months; P 0.05 ; . In women with subfertility attributed to endometrioma: Cystectomy increased the pregnancy rate 66.7% v 23.5%; odds ratio 8.25, 1.15 to 59; P 0.05 ; . Harms The trial reported no intraoperative or postoperative complications in either group. Comment None.
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| Criteria and History : Historical Findings: - Medical etiology Physical Findings: - Weak, dizzy - Chest pain - Pulmonary edema - Altered Mental Status - Hemodynamically unstable ECG Findings: - Any underlying cardiac rhythm with a bradycardic rate Assessment: Cardiac Assessment Primary Interventions: O2 via most appropriate method Vascular Access Secondary Interventions: Epinephrine 0.01 mg kg 0.1 ml kg 1: 10, 000 ; IV IO - q min IF NO VASCULAR ACCESS, Epinephrine 0.1 mg kg 0.1 ml kg 1: 000 ; ET - q 3 min Atropine 0.02 mg kg IV ET IO - Minimum single dose 0.1 mg - Maximum single dose 0.5 mg for a pediatric patient - May be repeated x 1 and lasix.
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Has stronger activities in endometrial stromal cell proliferation than sera from healthy non-endometriotic women 5 ; . Recently, we identified tissue-specific anti-endometrial IgMs that were frequently found in the sera of endometriotic patients 10 ; . The IgM fractions in the sera of these patients stimulated proliferation of HHUA cells 10 ; . Keishi-bukuryo-gan therapy decreased serum levels of the tissue-specific anti-endometrial IgMs while neither GnRHa nor danazol therapy suppressed anti-endometrial IgM levels 10 ; . The results of the present study suggest that endometrial cell stimulatory effects by IgM fractions purified from the sera of an endometriotic patient might be inhibited by unknown serum factor s ; or masked within total serum effects. However, tissue-specific anti-endometrial IgMs can stimulate endometrial epithelial cell growth because sufficient tissue-specific IgMs can be trapped and enriched in endometrial tissues to stimulate cell proliferation of endometrial epithelial cells in vivo. Our previous study revealed that sera from endometriotic patients, but not from non-endometriotic women, have strong stromal cell survival activities 5 ; . In the present study, however, not only the sera from endometriotic patients, but also those from non-endometriotic women, showed cell survival activities against Fas-mediated apoptosis of HHUA cells. Although Keishi-bukuryo-gan therapy, but not GnRHa or danazol therapy, suppresses endometrial stromal cell survival in the sera of endometriotic patients 5 ; , Keishi-bukuryo-gan, GnRHa and danazol therapy did not affect serum inhibitory activities of both endometriotic and non-endometriotic sera against Fas-mediated apoptosis in HHUA cells. From these results, it seems that the stromal cell survival factor s ; in serum inhibited by Keishi-bukuryo-gan therapy are distinct and levitra.
All medicines may have some side effects or risks associated with them.
Although no single nonpharmacologic therapy has been shown to be superior to another, a building body of evidence now shows the individual effectiveness of each of these treatments and lisinopril.
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Danazol also is used in fibrocystic breast disease to reduce breast pain, ten phenergan promethazine ; treats, nausea and vomiting and meridia and danazol.
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A cmpmedica web site homepage current issue subscriptions archives calendar classifieds about us june 2007 e-mail us get our newsletter review our patient guide april 04, 2006 mental notes slow-release adhd treatment may thwart risk of abuse by: p and mesterolone.
Porell, Frank W., and Helen B. Miltiades. Access to care and functional status change among aged Medicare beneficiaries. Journal of Gerontology: Social Sciences 56B 2 ; : S69-S83, March 2001.
Dropped sharply among white and black women in the United States and Canada, but it remains a serious concern. In the United States, almost 10, 400 cases of cervical cancer are diagnosed yearly, and over 3, 700 deaths per year are expected from the disease. If diagnosed early, invasive cervical cancer is highly treatable. The 5-year survival rate for U.S. women is 73%. Neither menopause nor hormone therapy used for menopause symptoms has been linked to increased cervical cancer risk. The primary causes of cervical cancer are specific types of human papillomavirus HPV ; , an infection acquired primarily through sexual relations. Women who began having sexual intercourse at an early age or who have many sexual partners are at increased risk. However, a woman may be infected with HPV even if she has only one sexual partner. Importantly, HPV infections are common in healthy, sexually active women and only rarely result in cervical cancer. Persistence of the infection and progression to cancer may be influenced by many factors, such as smoking, poor nutrition, and a weak immune system such as from HIV infection ; . In both men and women, HPV infection is sometimes associated with benign noncancerous ; growths in the genital area, called condylomata or genital warts. Most women who carry the virus have no signs or symptoms of HPV. A vaccine to prevent cancer-related types of HPV has been approved in the United States and Canada for use in adolescents. Studies are underway in older women to determine if the vaccine will benefit them. The Pap smear is a screening test to detect abnormal change in the cells of the cervix. It is a simple office procedure in which cells.
Prevent the onset of targeted conditions. Identify and treat asymptomatic patients who have risk factors or preclinical disease but in whom the condition has not become clinically apparent. Establish a consistent assessment schedule and indicators. Monitor the health and medical needs of the patient. Provide education and recommended screenings and interventions to the patient parent. Reassure the patient parent. Assess the patient's well-being. Detect medical and psychosocial complications and institute indicated interventions.
The effectiveness of the gnrh agonists is comparable to provera and danazol with respect to treatment of the pain associated with endometriosis.
Region C DMERC will offer an online workshop to provide clarification on the articles in this DMERC Medicare Advisory. The course will be offered on April 10 at 2: p.m. Eastern Time. For online workshop registration and attendance instructions, see "Online Learning Events -- How to Register" in this Advisory. The course name for this workshop is "DMERC Spring 2007 Medicare Advisory and darvon.
1. 2. 3. Bastuji, H. & Jouvet, M. 1988 ; Prog. Neuropsychopharmacol. Biol. Psychiatry 12, 695700. Duteil, J., Rambert, F. A., Pessonnier, J., Hermant, J. F., Gombert, R. & Assous, E. 1990 ; Eur. J. Pharmacol. 180, 4958. Hermant, J. F., Rambert, F. A. & Duteil, J. 1991 ; Psychopharmacology 103, 2832. Lin, J. S., Roussel, B., Akaoka, H., Fort, P., Debilly, G. & Jouvet, M. 1992 ; Brain Res. 591, 319326. Morgan, J. I. & Curran, T. 1989 ; Trends Neurosci. 12, 459462. Morgan, J. I. & Curran, T. 1991 ; Annu. Rev. Neurosci. 14, 421451. Sheng, M. & Greenberg, M. E. 1990 ; Neuron 4, 477485. Hunt, S. P., Pini, A. & Evan, G. 1989 ; Nature London ; 328, 632634. Ceccatelli, S., Villar, M. J., Goldstein, M. & Hokfelt, T. 1989 ; Proc. Natl. Acad. Sci. USA 86, 95699573. Fritschy, J. M., Frondoza, C. G. & Grzanna, R. 1991 ; Brain Res. 562, 4856. Young, S. T., Porrino, L. J. & Iadarola, M. J. 1991 ; Proc. Natl. Acad. Sci. USA 88, 12911295. Pompeiano, M., Cirelli, C. & Tononi, G. 1992 ; Arch. Ital. Biol. 130, 325335. Pompeiano, M., Cirelli, C. & Tononi, G. 1994 ; J. Sleep Res. 3, 8096. Shiromani, P. J., Kilduff, T. S., Bloom, F. E. & McCarley, R. W. 1992 ; Brain Res. 580, 351357. Yamuy, J., Mancillas, J. R., Morales, F. R. & Chase, M. H. 1993 ; J. Neurosci. 13, 27032718. Bleier, R. 1961 ; The Hypothalamus of the Cat: A Cytoarchitectonic Atlas in the Horsley-Clarke Co-ordinate System Johns Hopkins Univ. Press, Baltimore ; . Saper, C. B., Swanson, L. W. & Cowan, W. M. 1978 ; J. Comp. Neurol. 182, 575600. Berman, A. L. & Jones, E. G. 1982 ; The Thalamus and Basal Telencephalon of the Cat: A Cytoarchitectonic Atlas With Stereotaxic Coordinates Univ. of Wisconsin Press, Madison ; . Ledoux, L., Sastre, J. P., Buda, C., Luppi, P. H. & Jouvet, M. 1996 ; Brain Res. 735, 108118. Sherin, J. E., Shiromani, P. J., McCarley, R. W. & Saper, C. B. 1996 ; Science 271, 216219. Jones, B. E. 1989 ; in Principles and Practice of Sleep Medicine, eds. Kryger, M. H., Roth, T. & Dement, W. C. Saunders, Philadelphia ; , pp. 121138. Lin, J. S., Hou, Y., Sakai, K. & Jouvet, M. 1996 ; J. Neurosci. 16, 15231537. Hyman, S. E. 1996 ; Neuron 16, 901904. Graybiel, A. M., Moratalla, R. & Robertson, H. A. 1990 ; Proc. Natl. Acad. Sci. USA 87, 69126916. Jonansson, B., Lindstrom, K. & Fredholm, B. B. 1994 ; Neuroscience 59, 837849. Wang J. Q., Smith, A. J. W. & McGinty, J. F. 1995 ; Neuroscience 68, 8395. Swanson, L. W. 1982 ; Brain Res. Bull. 9, 321353. Bjorklund, A. & Lindvall, O. 1984 ; in Handbook of Chemical Neuroanat omy, eds. Bjorklund, A. & Hokfelt, T. Elsevier, Amsterdam ; , pp. 55121. Hughes, P. & Dragunow, M. 1995 ; Pharmacol. Rev. 47, 133178. Risold, P. Y., Canteras, N. S. & Swanson, L. W. 1994 ; J. Comp. Neurol. 348, 140. Nauta, W. J. H. 1946 ; J. Neurophysiol. 9, 285361. Lin, J. S., Sakai, K., Vanni-Mercier, G. & Jouvet, M. 1989 ; Brain Res. 479, 225240. Sallanon, M., Denoyer, M., Kitahama, K., Aubert, C., Gay, N. & Jouvet, M. 1989 ; Neuroscience 32, 669683. Lin, J. S., Sakai, K. & Jouvet, M. 1994 ; Eur. J. Neurosci. 6, 618625. Krilowiicz, B. L., Szymusiak, R. & McGinty, D. 1995 ; Brain Res. 668, 3038. Morgane, J. P. & Ranksepp, J. 1979 ; Handbook of Hypothalamus Dekker, New York ; , Vol. 1. Gritti, I., Mainville, L. & Jones, B. E. 1994 ; J. Comp. Neurol. 339, 251268. Kitahama, K., Sallanon, M., Okamura, H., Jeffard, M. & Jouvet, M. 1989 ; C.R. Acad. Sci. Ser. 3 308, 507511. Harlan, R. E., Shivers, B. D., Romano, G. J., Howlls, R. D. & Pfaff, D. W. 1987 ; J. Comp. Neurol. 258, 159184. Tanganelli, S., Fuxe, K., Ferraro, L., Janson, A. M. & Bianchi, C. 1992 ; Naunyn-Schmiedeberg's Arch. Pharmacol. 345, 461465. Tanganelli, S., Mora, M. P., Ferraro, L., Mendez-Franco, J., Beani, L., Rambert, F. & Fuxe, K. 1995 ; Eur. J. Pharmacol. 273, 6371. Vincent, S. R., Hokfelt, T., Skirboll, L. R. & Wu, J. Y. 1983 ; Science 220, 13091311. Freund, T. F. & Antal, M. 1988 ; Nature London ; 361, 170173. Freund, T. F. & Meskenaite, V. 1992 ; Proc. Natl. Acad. Sci. USA 89, 738742. Smythe, J. W., Colom, L. V. & Bland, B. H. 1992 ; Neurosci. Biobehav. Rev. 16, 289308.
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